Ectodermal dysplasia: Case report and molecular review

Anubhuti Sood; Deepika Mishra

Anubhuti Sood Senior Resident, Department of Oral Pathology and Microbiology, Centre for Dental education and Research, All India Institute of Medical Sciences, Delhi, India.
Deepika Mishra Associate Professor, Department of Oral Pathology and Microbiology, Center for Dental Education and Research, All India Institute of Medical Sciences, Delhi

Keywords: hypohidrotic, hereditary disorders, Ectodermal dysplasia

Abstract

The term ‘Ectodermal dysplasia’ refers to a group of heterogenous hereditary disorders characterized by abnormalities in ectodermal derivatives. There have been a number of classifications over time for ectodermal dysplasias given its varied presentation. However, the recent clinical-functional classification by Priolo has given due cognizance to the biopathogenetic mechanisms of this disorder. This paper presents a case report of hypohidrotic ectodermal dysplasia and focuses on the various genes and their pathways identified in the past decade.